Cart
sales@molnova.com
VU 0364439
CAS No. 1246086-78-1
VU 0364439( VU0364439, VU-0364439, VU 0364439 )
Catalog No. M17215 CAS No. 1246086-78-1
VU 0364439 is a mGlu4 positive allosteric modulator (C50: 19.8 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 52 | In Stock |
|
| 5MG | 86 | In Stock |
|
| 10MG | 124 | In Stock |
|
| 25MG | 237 | In Stock |
|
| 50MG | 413 | In Stock |
|
| 100MG | 591 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameVU 0364439
-
NoteResearch use only, not for human use.
-
Brief DescriptionVU 0364439 is a mGlu4 positive allosteric modulator (C50: 19.8 nM).
-
DescriptionVU0364439 is a positive allosteric modulator (PAM) of mGlu4 receptors (EC50 = 19.8 nM in vitro for human mGlu4).
-
In Vitro——
-
In Vivo——
-
SynonymsVU0364439, VU-0364439, VU 0364439
-
PathwayCytoskeleton/Cell Adhesion Molecules
-
TargetMicrotubule/Tubulin
-
RecptormGluR4
-
Research AreaNeurological Disease
-
Indication——
Chemical Information
-
CAS Number1246086-78-1
-
Formula Weight422.29
-
Molecular FormulaC18H13Cl2N3O3S
-
Purity>98% (HPLC)
-
SolubilityDMSO : 50 mg/mL. 118.40 mM;
-
SMILESc1ccc(c(c1)NS(=O)(=O)c1c(cc(cc1)NC(=O)c1ccccn1)Cl)Cl
-
Chemical NameN-[3-Chloro-4-[[(2-chlorophenyl)amino]sulfonyl]phenyl]-2-pyridinecarboxamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Engers DW, et al. Bioorg Med Chem Lett, 2010, 20(17), 5175-5178.
molnova catalog
related products
-
DJ101
A novel potent and metabolically stable tubulin inhibitor.
-
KIF18A-IN-2
KIF18A-IN-2 is an inhibitor of mitotic kinesin Kif18A with IC50 of 28 nM and can be used in studies about chromosomal instability-associated vulnerabilities.
-
Triclabendazole
Triclabendazole is a benzimidazole, it binds to tubulin impairing intracellular transport mechanisms and interferes with protein synthesis.
